ARB Plus

ARB Plus

telmisartan + hydrochlorothiazide

Manufacturer:

Corona Remedies

Distributor:

Iberica Verheilen
Concise Prescribing Info
Contents
Telmisartan 40 mg, hydrochlorothiazide 12.5 mg
Indications/Uses
Essential HTN. In adults whose BP is not adequately controlled on telmisartan alone.
Dosage/Direction for Use
Contraindications
Hypersensitivity to telmisartan, hydrochlorothiazide, or other sulfonamide-derived substances. Cholestasis & biliary obstructive disorders. Refractory hypokalaemia, hypercalcaemia. Concomitant use w/ aliskiren in patients w/ DM or renal impairment (GFR <60 mL/min/1.73 m2). Severe hepatic & renal (CrCl <30 mL/min) impairment. Pregnancy (2nd & 3rd trimester)
Special Precautions
May impair glucose tolerance or hypoglycaemia may occur in diabetics under insulin or antidiabetic therapy. Monitor blood glucose. Pregnancy (1st trimester). Not recommended during lactation. Telmisartan: Do not give to patients w/ cholestasis, biliary obstructive disorders or severe hepatic insufficiency. Increased risk of severe hypotension & renal insufficiency in patients w/ bilateral renal artery stenosis or stenosis of the artery to a single functioning kidney. Hydrochlorothiazide: May manifest latent DM during therapy.
Adverse Reactions
Dizziness. Telmisartan: Abnormal hepatic function/liver disorder; sepsis; ILD.
Drug Interactions
May reduce diuretic, natriuretic, & antihypertensive effects w/ NSAIDs (ie, ASA at anti-inflammatory dosage regimens, COX-2 inhibitors, & non-selective NSAIDs). Telmisartan: Dual blockade of the renin-aldosterone system (RAAS) w/ aliskiren. Reversible increase in serum conc & toxicity of lithium. Hydrochlorothiazide: Thiazide-induced hypokalaemia or hypomagnesaemia favors the onset of digitalis-induced arrhythmia. May enhance hyperglycaemic effects of β-blockers & diazoxide. May increase bioavailability w/ anticholinergic agents (eg, atropine, biperiden). May aggravate orthostatic hypotension w/ alcohol, barbiturates, narcotics, or antidepressants.
MIMS Class
Angiotensin II Antagonists / Diuretics
Presentation/Packing
Form
ARB Plus FC tab
Packing/Price
30's
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